Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG1140
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG1140 (FBgn0035298).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -0.5307 1.6906 2.268116 -1.1551 -1.213462 -1.8416 4.05367 1.343582
    Affimetrix absolute value 8.159 8.373 9.349 8.181 8.479 7.684 10.558 8.66
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: 3-oxoacid CoA-transferase activity.
Based on sequence similarity, it is predicted to be involved in the biological process: ketone body catabolic process.
9 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: 3-oxoacid CoA-transferase; 3-oxoacid CoA-transferase, subunit A; 3-oxoacid CoA-transferase, subunit B; Coenzyme A transferase; Coenzyme A transferase active site; Coenzyme A transferase binding site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 and 18-24 hour embryonic stages, during early larval stages.