Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Gef64C
Flybase description The gene Guanine nucleotide exchange factor GEF64C is referred to in FlyBase by the symbol Dmel\Gef64C (CG32239, FBgn0035574).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -60.6681 -29.1827 -56.603107 -64.5696 -79.61029 -73.2479 -15.22479 -57.247965
    Affimetrix absolute value 2.51 2.762 2.37 2.383 2.447 2.369 4.745 2.432
    Affymetric present call in "x" number of chips 0 1 0 0 0 0 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: guanyl-nucleotide exchange factor activity.
There is experimental evidence that it is involved in the biological process: inter-male aggressive behavior; axon guidance; spiracle morphogenesis, open tracheal system.
32 alleles are reported.
The phenotypes of these alleles are annotated with: commissure; ventral nerve cord commissure; longitudinal connective; mesothoracic tergum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Dbl homology (DH) domain; Pleckstrin homology domain; Rho GTP exchange factor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed at stages throughout the pupal period.