Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG7376
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG7376 (FBgn0035689).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -35.9695 -19.3904 -33.321665 -31.0798 -49.501614 -30.1654 -29.48947 -43.880168
    Affimetrix absolute value 3.244 3.349 3.129 3.479 3.185 3.683 3.681 2.865
    Affymetric present call in "x" number of chips 2 3 0 1 1 1 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding; zinc ion binding; ATP binding; helicase activity.
There is experimental evidence that it is involved in the biological process: neurogenesis.
4 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: DEAD-like helicase; Helicase, C-terminal; SNF2-related; Tetratricopeptide repeat; Tetratricopeptide repeat-containing; Tetratricopeptide-like helical; Zinc finger, C3HC4 RING-type; Zinc finger, FYVE/PHD-type; Zinc finger, PHD-type; Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.
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