Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG5946
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG5946 (FBgn0036211).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.7869 3.4728 2.36688 1.8632 2.103359 1.843 1.35431 2.20056
    Affimetrix absolute value 9.24 9.392 9.419 9.284 9.83 9.442 8.976 9.376
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: cytochrome-b5 reductase activity.
There is experimental evidence that it is involved in the biological process: inter-male aggressive behavior.
14 alleles are reported.
The phenotype of these alleles is annotated with: trichogen cell.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Ferredoxin reductase-type FAD-binding domain; Flavoprotein pyridine nucleotide cytochrome reductase; NADH:cytochrome b5 reductase (CBR); Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase, FAD-binding domain; Riboflavin synthase-like beta-barrel.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed during early larval stages.