Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Atg12
Flybase description The gene Autophagy-specific gene 12 is referred to in FlyBase by the symbol Dmel\Atg12 (CG10861, FBgn0036255).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.5916 -1.7592 -1.869676 -2.7011 -2.1794 -2.8948 -3.62168 -2.125265
    Affimetrix absolute value 7.742 6.811 7.286 6.97 7.644 7.037 6.703 7.156
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: autophagic cell death; autophagy; salivary gland cell autophagic cell death.
5 alleles are reported.
The phenotype of these alleles is annotated with: embryonic/larval salivary gland.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Autophagy-related protein 12.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.