Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Best4
Flybase description The gene Bestrophin 4 is referred to in FlyBase by the symbol Dmel\Best4 (CG7259, FBgn0036491).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -33.3461 -22.4626 -31.713367 -39.2592 -47.209026 -45.2938 -46.17149 -33.147589
    Affimetrix absolute value 3.358 3.147 3.215 3.099 3.212 3.062 3.022 3.245
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: anion channel activity.
Based on sequence similarity, it is predicted to be involved in the biological process: anion transport.
3 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Bestrophin; Bestrophin/UPF0187.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of no expression detected.
Peak expression observed within 06-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.
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