Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG7430
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG7430 (FBgn0036762).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.1865 3.3943 3.079325 6.7598 1.842174 1.8022 5.16446 3.346307
    Affimetrix absolute value 9.478 9.377 9.779 11.144 9.637 9.399 10.918 9.963
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: dihydrolipoyl dehydrogenase activity.
Based on sequence similarity, it is predicted to be involved in the biological process: glycine catabolic process; lipoamide metabolic process; tricarboxylic acid cycle.
4 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Dihydrolipoamide dehydrogenase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD/NAD-linked reductase, dimerisation; Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding domain; Pyridine nucleotide-disulphide oxidoreductase, class I, active site; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.