Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG13253
Flybase description The gene crimpy is referred to in FlyBase by the symbol Dmel\cmpy (CG13253, FBgn0037015).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -37.1006 -19.6784 -25.415482 -34.4403 -35.310469 -40.1788 -43.65705 -29.376172
    Affimetrix absolute value 3.208 3.333 3.557 3.284 3.629 3.234 3.112 3.403
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: insulin-like growth factor binding.
There is experimental evidence that it is involved in the biological process: negative regulation of BMP signaling pathway; BMP signaling pathway; neuromuscular junction development.
7 alleles are reported.
No phenotypic data is available.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Insulin-like growth factor-binding protein, IGFBP.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages.
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