Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG12972
Flybase description The gene earthbound 2 is referred to in FlyBase by the symbol Dmel\ebd2 (CG12972, FBgn0037076).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -18.7863 -5.8469 -5.180945 -4.2983 -5.732398 -4.236 -19.92502 -5.905762
    Affimetrix absolute value 4.178 5.079 5.806 6.302 6.267 6.486 4.247 5.708
    Affymetric present call in "x" number of chips 0 3 3 3 3 3 0 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding.
There is experimental evidence that it is involved in the biological process: adult somatic muscle development.
7 alleles are reported.
The phenotype of these alleles is annotated with: dorsal medial muscle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Centromere protein Cenp-B, DNA-binding domain 1; Helix-turn-helix, Psq-like; Homeodomain-like; Homeodomain-related; Pogo transposase / Cenp-B / PDC2, DNA-binding HTH domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period, in adult female stages.