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|Flybase description||The gene delta-1-Pyrroline-5-carboxylate dehydrogenase 1 is referred to in FlyBase by the symbol Dmel\P5CDh1 (CG7145, FBgn0037138).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: 1-pyrroline-5-carboxylate dehydrogenase activity.
There is experimental evidence that it is involved in the biological process: proline metabolic process; mitochondrion organization.
15 alleles are reported.
The phenotype of these alleles is annotated with: mitochondrion.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Aldehyde dehydrogenase domain; Aldehyde dehydrogenase, C-terminal; Aldehyde dehydrogenase, N-terminal; Aldehyde dehydrogenase, conserved site; Aldehyde/histidinol dehydrogenase; Delta-1-pyrroline-5-carboxylate dehydrogenase 1.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed during early larval stages, during late pupal stages, in stages of adults of both sexes.