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|Flybase description||The gene pancreatic eIF-2α kinase is referred to in FlyBase by the symbol Dmel\PEK (CG2087, FBgn0037327).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: elongation factor-2 kinase activity.
There is experimental evidence that it is involved in the biological process: regulation of G2/M transition of mitotic cell cycle.
16 alleles are reported.
The phenotypes of these alleles are annotated with: eye disc; eye disc posterior to the morphogenetic furrow.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Pyrrolo-quinoline quinone beta-propeller repeat; Quinonprotein alcohol dehydrogenase-like; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.