Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Hcs
Flybase description The gene Holocarboxylase synthetase is referred to in FlyBase by the symbol Dmel\Hcs (CG14670, FBgn0037332).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -5.9815 -3.5953 -5.1202 -5.819 -9.084784 -7.381 -8.01571 -8.030577
    Affimetrix absolute value 5.835 5.784 5.873 5.847 5.636 5.681 5.565 5.323
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity.
There is experimental evidence that it is involved in the biological process: response to heat.
7 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Biotin protein ligase, C-terminal; Biotin--acetyl-CoA-carboxylase ligase; Biotin/lipoate A/B protein ligase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.