Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name skap
Flybase description The gene skpA associated protein is referred to in FlyBase by the symbol Dmel\skap (CG11963, FBgn0037643).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.0382 2.8738 1.916853 4.9832 -0.328093 2.2205 8.18141 2.160581
    Affimetrix absolute value 9.984 9.132 9.068 10.701 8.759 9.709 11.575 9.27
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: succinate-CoA ligase (ADP-forming) activity.
There is experimental evidence that it is involved in the biological process: regulation of centrosome duplication; mitotic spindle organization.
6 alleles are reported.
No phenotypic data is available.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp fold; ATP-grasp fold, subdomain 1; ATP-grasp fold, subdomain 2; ATP-grasp fold, succinyl-CoA synthetase-type; Succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase, beta subunit, conserved site; Succinyl-CoA synthetase-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.