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|Flybase description||The gene FBX011 ortholog is referred to in FlyBase by the symbol Dmel\FBX011 (CG9461, FBgn0037760).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: ubiquitin-protein ligase activity; zinc ion binding.
There is experimental evidence that it is involved in the biological process: regulation of gene silencing by RNA; siRNA loading onto RISC involved in chromatin silencing by small RNA.
8 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Carbohydrate-binding/sugar hydrolysis domain; F-box domain, Skp2-like; F-box domain, cyclin-like; Parallel beta-helix repeat; Parallel beta-helix repeat-2; Pectin lyase fold; Pectin lyase fold/virulence factor; Zinc finger, N-recognin.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.