Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name foxo
Flybase description The gene forkhead box, sub-group O is referred to in FlyBase by the symbol Dmel\foxo (CG3143, FBgn0038197).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -7.2893 -2.9222 -2.859766 -6.1153 -6.75099 -6.235 -2.02071 -4.891342
    Affimetrix absolute value 5.543 6.129 6.672 5.785 6.023 5.927 7.57 6.025
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding.
There is experimental evidence for 18 unique biological process terms, many of which group under: biological regulation; response to stress; regulation of insulin receptor signaling pathway; cellular process; regulation of growth; response to DNA damage stimulus; cellular component organization or biogenesis; response to bacterium; response to nutrient levels; determination of adult lifespan; sensory organ development; primary metabolic process.
37 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system subdivision; organ system; adult; external compound sense organ; adult segment; region of integument; thoracic segment; peripheral nervous system; ectoderm derivative; muscle cell; mushroom body neuroblast; portion of tissue.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Transcription factor, fork head; Transcription factor, fork head, conserved site; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late pupal stages.