Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Npc2b
Flybase description The gene Niemann-Pick type C-2b is referred to in FlyBase by the symbol Dmel\Npc2b (CG3153, FBgn0038198).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 14.4013 4.1907 -4.99365 -5.6051 -6.803798 -2.2282 5.45266 0.310766
    Affimetrix absolute value 12.246 9.675 5.866 5.93 6.002 7.434 10.995 8.222
    Affymetric present call in "x" number of chips 3 3 3 3 1 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sterol binding.
There is experimental evidence that it is involved in the biological process: sterol transport; ecdysteroid biosynthetic process.
9 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Immunoglobulin E-set; MD-2-related lipid-recognition.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed at stages throughout the pupal period.