Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name HtrA2
Flybase description The gene HtrA2 is referred to in FlyBase by the symbol Dmel\HtrA2 (CG8464, FBgn0038233).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -11.3296 -6.2605 -9.195455 -7.1864 -14.132773 -8.5039 -5.97581 -11.474132
    Affimetrix absolute value 4.946 4.974 5.032 5.543 4.97 5.476 5.994 4.821
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: peptidase activity.
There is experimental evidence that it is involved in the biological process: mitochondrion organization.
9 alleles are reported.
The phenotypes of these alleles are annotated with: eye; spermatozoon.
It has one annotated transcript and one annotated polypeptide.
Protein features are: PDZ/DHR/GLGF; Peptidase S1/S6, chymotrypsin/Hap; Peptidase S1C, HrtA/DegP2/Q/S; Peptidase cysteine/serine, trypsin-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in adult male stages.