Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Sra-1
Flybase description The gene specifically Rac1-associated protein 1 is referred to in FlyBase by the symbol Dmel\Sra-1 (CG4931, FBgn0038320).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.1769 2.712 1.819533 1.6714 0.615566 1.5653 0.74488 0.755192
    Affimetrix absolute value 8.174 9.047 9.015 9.107 9.083 9.203 8.973 8.684
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: Rho GTPase binding.
There is experimental evidence that it is involved in the biological process: regulation of cell shape; regulation of synapse organization; axon guidance; cell projection assembly; cortical actin cytoskeleton organization; phagocytosis, engulfment.
19 alleles are reported.
The phenotypes of these alleles are annotated with: commissure; eye; bouton; intersegmental nerve; embryonic/larval neuromuscular junction; longitudinal connective; microchaeta; ommatidium; synapse; axon.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Cytoplasmic FMR1-interacting; Cytoplasmic FMR1-interacting, subgroup.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages.