Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ns1
Flybase description The gene nucleostemin 1 is referred to in FlyBase by the symbol Dmel\ns1 (CG3983, FBgn0038473).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.3832 -1.9235 -3.049531 -2.6861 -3.698292 -4.2334 -3.77494 -3.554467
    Affimetrix absolute value 7.156 6.698 6.573 6.971 6.875 6.504 6.656 6.429
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: GTP binding.
There is experimental evidence that it is involved in the biological process: regulation of insulin receptor signaling pathway; regulation of multicellular organism growth.
4 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: GNL3L/Grn1 putative GTPase; GTP-binding domain, HSR1-related; GTP-binding protein, orthogonal bundle domain; GTP1/OBG.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages, during early larval stages.