Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Prx5037
Flybase description The gene Peroxiredoxin 3 is referred to in FlyBase by the symbol Dmel\Prx3 (CG5826, FBgn0038519).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.5275 2.1092 2.511043 2.4488 1.763975 2.2034 3.26726 2.018178
    Affimetrix absolute value 8.975 8.688 9.47 9.673 9.545 9.696 10.254 9.204
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: thioredoxin peroxidase activity.
There is experimental evidence that it is involved in the biological process: cell redox homeostasis; determination of adult lifespan; negative regulation of apoptosis; hydrogen peroxide catabolic process; phagocytosis, engulfment.
4 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; Peroxiredoxin, C-terminal; Thioredoxin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed during early larval stages.