Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name endoA
Flybase description The gene endophilin A is referred to in FlyBase by the symbol Dmel\endoA (CG14296, FBgn0038659).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.0532 -1.8858 -3.888995 -3.9196 -6.48055 -4.4726 -3.36028 -5.366765
    Affimetrix absolute value 6.396 6.716 6.235 6.427 6.11 6.403 6.826 5.945
    Affymetric present call in "x" number of chips 3 3 3 3 2 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: lysophosphatidic acid acyltransferase activity.
There is experimental evidence that it is involved in the biological process: synaptic vesicle endocytosis; regulation of synapse structure and activity.
33 alleles are reported.
The phenotypes of these alleles are annotated with: eye; interommatidial bristle; presynaptic active zone; bouton; motor neuron; embryonic/larval neuromuscular junction; wing; ommatidium; synapse; synaptic vesicle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: BAR; Spectrin alpha chain, SH3 domain; Src homology-3 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes.