Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name MED25
Flybase description The gene Mediator complex subunit 25 is referred to in FlyBase by the symbol Dmel\MED25 (CG12254, FBgn0038760).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -9.7486 -5.3503 -7.308782 -9.1315 -12.495821 -10.5363 -9.06038 -9.289971
    Affimetrix absolute value 5.152 5.2 5.317 5.198 5.136 5.181 5.38 5.061
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: RNA polymerase II transcription cofactor activity.
There is experimental evidence that it is involved in the biological process: nervous system development; regulation of antimicrobial peptide biosynthetic process.
5 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Mediator complex, subunit Med25, NR box; Mediator complex, subunit Med25, PTOV activation and synapsin 2; Mediator complex, subunit Med25, von Willebrand factor type A.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.