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|Flybase description||The gene sar1 is referred to in FlyBase by the symbol Dmel\sar1 (CG7073, FBgn0038947).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: GTPase activity; GTP binding.
There is experimental evidence that it is involved in the biological process: chitin-based cuticle development; chitin-based larval cuticle pattern formation; endoplasmic reticulum organization; negative regulation of dendrite morphogenesis; positive regulation of cuticle pigmentation; larval chitin-based cuticle development; embryonic heart tube development.
12 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; sarcomere; cardioblast; embryonic pericardial cell; embryonic/larval epidermis.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Small GTP-binding protein domain; Small GTPase superfamily, ARF/SAR type; Small GTPase superfamily, SAR1-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.