Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Nrx-1
Flybase description The gene Neurexin 1 is referred to in FlyBase by the symbol Dmel\Nrx-1 (CG7050, FBgn0038975).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -11.88 -10.7793 -12.311718 -15.6795 -26.708906 -21.429 -12.40738 -17.497889
    Affimetrix absolute value 4.838 4.203 4.587 4.42 4.025 4.15 4.958 4.248
    Affymetric present call in "x" number of chips 3 0 0 0 0 1 1 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: synapse assembly; synaptic transmission; associative learning; synapse organization.
21 alleles are reported.
The phenotypes of these alleles are annotated with: bouton; neuromuscular junction; type I bouton; synapse.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Concanavalin A-like lectin/glucanase; Concanavalin A-like lectin/glucanase, subgroup; EGF; Epidermal growth factor-like; Epidermal growth factor-like, type 3; Laminin G domain; Laminin G, subdomain 2.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.