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|Flybase description||The gene Dicer-1 is referred to in FlyBase by the symbol Dmel\Dcr-1 (CG4792, FBgn0039016).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; bidentate ribonuclease III activity.
There is experimental evidence for 11 unique biological process terms, many of which group under: biological regulation; cellular component organization or biogenesis; gene silencing; gene expression; multicellular organism reproduction; multicellular organismal development; gene silencing by miRNA; gamete generation; dsRNA fragmentation; RNA interference.
22 alleles are reported.
The phenotypes of these alleles are annotated with: oocyte; embryonic/larval neuromuscular junction.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Argonaute/Dicer protein, PAZ; Dicer double-stranded RNA-binding fold; Double-stranded RNA-binding; Helicase, C-terminal; Ribonuclease III.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.