Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Dcr-1
Flybase description The gene Dicer-1 is referred to in FlyBase by the symbol Dmel\Dcr-1 (CG4792, FBgn0039016).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -19.1786 -7.4664 -13.444522 -11.8552 -28.277238 -14.9858 -18.22997 -15.417957
    Affimetrix absolute value 4.159 4.728 4.466 4.852 4.01 4.668 4.427 4.35
    Affymetric present call in "x" number of chips 3 3 2 3 2 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; bidentate ribonuclease III activity.
There is experimental evidence for 11 unique biological process terms, many of which group under: biological regulation; cellular component organization or biogenesis; gene silencing; gene expression; multicellular organism reproduction; multicellular organismal development; gene silencing by miRNA; gamete generation; dsRNA fragmentation; RNA interference.
22 alleles are reported.
The phenotypes of these alleles are annotated with: oocyte; embryonic/larval neuromuscular junction.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Argonaute/Dicer protein, PAZ; Dicer double-stranded RNA-binding fold; Double-stranded RNA-binding; Helicase, C-terminal; Ribonuclease III.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.