Flygut: an atlas of the Drosophila adult midgut

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Gene name SPE
Flybase description The gene Spatzle-Processing Enzyme is referred to in FlyBase by the symbol Dmel\SPE (CG16705, FBgn0039102).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.886 -2.8804 -43.687381 -52.952 -63.798934 -39.6215 -7.20698 -12.312751
    Affimetrix absolute value 9.317 6.106 2.762 2.678 2.783 3.276 5.938 4.645
    Affymetric present call in "x" number of chips 3 3 0 0 0 0 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: serine-type endopeptidase activity.
There is experimental evidence that it is involved in the biological process: defense response to fungus; zymogen activation; innate immune response; positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria; Toll signaling pathway; humoral immune response; defense response to Gram-positive bacterium; defense response to Gram-negative bacterium; defense response; positive regulation of Toll signaling pathway.
12 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; embryonic/larval fat body; embryonic/larval hemocoel.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Peptidase S1/S6, chymotrypsin/Hap; Peptidase S1/S6, chymotrypsin/Hap, active site; Peptidase S1A, chymotrypsin-type; Peptidase cysteine/serine, trypsin-like; Proteinase, regulatory CLIP domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed during late pupal stages, in stages of adults of both sexes.