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|Flybase description||The gene spastin is referred to in FlyBase by the symbol Dmel\spas (CG5977, FBgn0039141).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: ATPase activity.
There is experimental evidence that it is involved in the biological process: locomotory behavior; hemocyte migration; microtubule cytoskeleton organization; positive regulation of microtubule depolymerization.
28 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; organ system subdivision; peripheral nervous system; organelle; multicellular structure; intracellular non-membrane-bounded organelle; cell part; intracellular organelle part; intracellular organelle; cytoplasmic part; multidendritic neuron; adult segment.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: ATPase, AAA+ type, core; ATPase, AAA-type, conserved site; ATPase, AAA-type, core; MIT.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages, during early pupal stages, in adult female stages.