Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name polybromo
Flybase description The gene polybromo is referred to in FlyBase by the symbol Dmel\polybromo (CG11375, FBgn0039227).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -17.7216 -7.95 -14.017605 -15.9408 -20.042321 -14.3509 -14.52594 -17.117513
    Affimetrix absolute value 4.261 4.635 4.379 4.423 4.459 4.792 4.756 4.173
    Affymetric present call in "x" number of chips 1 3 1 3 2 3 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding; zinc ion binding.
There is experimental evidence that it is involved in the biological process: eggshell chorion assembly; negative regulation of chromatin silencing; vitelline membrane formation involved in chorion-containing eggshell formation; imaginal disc-derived leg morphogenesis.
8 alleles are reported.
The phenotypes of these alleles are annotated with: chorion; vitelline membrane.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Bromo adjacent homology (BAH) domain; Bromodomain; Bromodomain, conserved site; High mobility group, HMG1/HMG2; High mobility group, superfamily; Zinc finger, C2H2-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.