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|Flybase description||The gene polybromo is referred to in FlyBase by the symbol Dmel\polybromo (CG11375, FBgn0039227).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: DNA binding; zinc ion binding.
There is experimental evidence that it is involved in the biological process: eggshell chorion assembly; negative regulation of chromatin silencing; vitelline membrane formation involved in chorion-containing eggshell formation; imaginal disc-derived leg morphogenesis.
8 alleles are reported.
The phenotypes of these alleles are annotated with: chorion; vitelline membrane.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Bromo adjacent homology (BAH) domain; Bromodomain; Bromodomain, conserved site; High mobility group, HMG1/HMG2; High mobility group, superfamily; Zinc finger, C2H2-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.