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|Flybase description||This gene is referred to in FlyBase by the symbol Dmel\CG11876 (FBgn0039635).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: pyruvate dehydrogenase (acetyl-transferring) activity.
There is experimental evidence that it is involved in the biological process: cytoplasmic microtubule organization.
4 alleles are reported.
The phenotype of these alleles is annotated with: mitochondrion.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Domain of unknown function DUF1713, mitochondria; Transketolase, C-terminal; Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II; Transketolase-like, C-terminal; Transketolase-like, pyrimidine-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.