Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name CG11876
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG11876 (FBgn0039635).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.5137 -1.1871 0.319865 1.3683 -0.322977 -1.2496 1.15098 0.300635
    Affimetrix absolute value 7.811 7.374 8.161 8.835 8.772 8.243 8.75 8.201
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: pyruvate dehydrogenase (acetyl-transferring) activity.
There is experimental evidence that it is involved in the biological process: cytoplasmic microtubule organization.
4 alleles are reported.
The phenotype of these alleles is annotated with: mitochondrion.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Domain of unknown function DUF1713, mitochondria; Transketolase, C-terminal; Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II; Transketolase-like, C-terminal; Transketolase-like, pyrimidine-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.