Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CDase
Flybase description The gene Ceramidase is referred to in FlyBase by the symbol Dmel\CDase (CG1471, FBgn0039774).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -9.5465 -6.0536 -2.178669 -5.3821 3.387039 -0.8408 -50.782 1.808952
    Affimetrix absolute value 5.255 5.074 7.058 5.972 10.496 8.077 2.947 9.064
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 0 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: ceramidase activity.
There is experimental evidence that it is involved in the biological process: synaptic transmission; sphingolipid metabolic process; photoreceptor cell maintenance; ceramide catabolic process; synaptic vesicle fusion to presynaptic membrane; hatching behavior; synaptic vesicle exocytosis.
11 alleles are reported.
The phenotypes of these alleles are annotated with: rhabdomere; eye disc; eye photoreceptor cell; synaptic vesicle.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Neutral/alkaline nonlysosomal ceramidase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed during early pupal stages.