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|Flybase description||The gene prolyl-4-hydroxylase-alpha NE1 is referred to in FlyBase by the symbol Dmel\PH4αNE1 (CG9728, FBgn0039780).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: procollagen-proline 4-dioxygenase activity.
Based on sequence similarity, it is predicted to be involved in the biological process: peptidyl-proline hydroxylation to 4-hydroxy-L-proline.
3 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Oxoglutarate/iron-dependent oxygenase; Prolyl 4-hydroxylase alpha-subunit, N-terminal; Prolyl 4-hydroxylase, alpha subunit; Tetratricopeptide-like helical.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.
Peak expression observed during early larval stages.