Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Trx-2
Flybase description The gene thioredoxin-2 is referred to in FlyBase by the symbol Dmel\Trx-2 (CG31884, FBgn0040070).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 11.8964 9.4075 4.83506 8.0155 5.575881 6.2995 5.2071 6.404499
    Affimetrix absolute value 11.978 10.85 10.446 11.39 11.233 11.213 10.925 10.918
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: disulfide oxidoreductase activity.
There is experimental evidence that it is involved in the biological process: cell redox homeostasis; determination of adult lifespan; response to DNA damage stimulus; response to oxidative stress.
19 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Thioredoxin; Thioredoxin domain; Thioredoxin, conserved site; Thioredoxin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.