Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name pkaap
Flybase description The gene pkaap is referred to in FlyBase by the symbol Dmel\pkaap (CG4132, FBgn0040079).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.8057 -3.1867 -7.791037 -6.8808 -11.807655 -8.6479 -2.55876 -9.191393
    Affimetrix absolute value 6.921 5.955 5.232 5.616 5.198 5.454 7.208 5.073
    Affymetric present call in "x" number of chips 3 2 0 3 1 2 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein kinase A binding.
Based on sequence similarity, it is predicted to be involved in the biological process: protein localization.
5 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Regulator of G protein signalling; Regulator of G protein signalling superfamily.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, in adult female stages.