Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Aplip1
Flybase description The gene APP-like protein interacting protein 1 is referred to in FlyBase by the symbol Dmel\Aplip1 (CG1200, FBgn0040281).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -52.6622 -26.5028 -41.276508 -41.3741 -55.759866 -50.2831 -56.00002 -43.847858
    Affimetrix absolute value 2.699 2.901 2.821 3.054 2.979 2.913 2.751 2.813
    Affymetric present call in "x" number of chips 0 1 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; protein kinase binding; kinesin binding.
There is experimental evidence that it is involved in the biological process: axon transport of mitochondrion; regulation of JNK cascade; retrograde synaptic vesicle transport; anterograde synaptic vesicle transport.
12 alleles are reported.
The phenotypes of these alleles are annotated with: mitochondrion; axon.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Phosphotyrosine interaction domain; Pleckstrin homology-type; Src homology-3 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 12-18 embryonic stages.