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|Flybase description||The gene RecQ4 is referred to in FlyBase by the symbol Dmel\RecQ4 (CG7487, FBgn0040290).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: DNA strand annealing activity; ATP-dependent DNA helicase activity; 3'-5' DNA helicase activity.
There is experimental evidence for 11 unique biological process terms, many of which group under: biological regulation; DNA repair; primary metabolic process; response to DNA damage stimulus; cellular macromolecule biosynthetic process; positive regulation of biological process; multicellular organism reproduction; nitrogen compound metabolic process; cellular biosynthetic process; positive regulation of cell proliferation; cellular component organization or biogenesis; multicellular organismal development; gamete generation.
23 alleles are reported.
The phenotypes of these alleles are annotated with: fat body; chorion; spiracle; salivary gland; egg; embryonic/larval brain; salivary gland imaginal ring.
It has one annotated transcript and one annotated polypeptide.
Protein features are: DEAD-like helicase; DNA helicase, ATP-dependent, RecQ type; DNA replication/checkpoint protein; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Zinc finger, CCHC-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.