Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name RecQ4
Flybase description The gene RecQ4 is referred to in FlyBase by the symbol Dmel\RecQ4 (CG7487, FBgn0040290).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -55.012 -32.2445 -43.768574 -43.1107 -66.215181 -49.8563 -52.18684 -48.660881
    Affimetrix absolute value 2.631 2.622 2.737 2.958 2.731 2.923 2.851 2.669
    Affymetric present call in "x" number of chips 0 0 0 0 0 1 1 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: DNA strand annealing activity; ATP-dependent DNA helicase activity; 3'-5' DNA helicase activity.
There is experimental evidence for 11 unique biological process terms, many of which group under: biological regulation; DNA repair; primary metabolic process; response to DNA damage stimulus; cellular macromolecule biosynthetic process; positive regulation of biological process; multicellular organism reproduction; nitrogen compound metabolic process; cellular biosynthetic process; positive regulation of cell proliferation; cellular component organization or biogenesis; multicellular organismal development; gamete generation.
23 alleles are reported.
The phenotypes of these alleles are annotated with: fat body; chorion; spiracle; salivary gland; egg; embryonic/larval brain; salivary gland imaginal ring.
It has one annotated transcript and one annotated polypeptide.
Protein features are: DEAD-like helicase; DNA helicase, ATP-dependent, RecQ type; DNA replication/checkpoint protein; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Zinc finger, CCHC-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.