Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Nhe2
Flybase description The gene Na+/H+ hydrogen exchanger 2 is referred to in FlyBase by the symbol Dmel\Nhe2 (CG9256, FBgn0040297).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -15.0752 -2.7947 -6.093631 -2.097 -13.727808 -23.595 -25.49519 -9.004449
    Affimetrix absolute value 4.515 6.139 5.603 7.354 5.015 4.002 3.893 5.132
    Affymetric present call in "x" number of chips 0 2 0 3 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: sodium:hydrogen antiporter activity.
It is reported to be involved in the biological process: regulation of pH.
19 alleles are reported.
The phenotypes of these alleles are annotated with: eye; embryonic/larval digestive system; embryonic/larval fat body; eye photoreceptor cell; ommatidium.
It has 9 annotated transcripts and 9 annotated polypeptides.
Protein features are: Cation/H+ exchanger; Cation/H+ exchanger, CPA1 family; Na+/H+ exchanger; Na+/H+ exchanger, isoforms 3/9.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-12 and 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult male stages.