Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name rols
Flybase description The gene rolling pebbles is referred to in FlyBase by the symbol Dmel\rols (CG32096, FBgn0041096).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -27.6785 -2.6659 -5.903011 -4.0435 -10.093166 -9.9935 -11.75076 -7.631953
    Affimetrix absolute value 3.622 6.24 5.623 6.386 5.448 5.281 5.019 5.342
    Affymetric present call in "x" number of chips 0 3 3 3 3 3 2 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: myoblast fusion.
45 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic anterior Malpighian tubule; embryonic/larval pharynx; embryonic Malpighian tubule; Malpighian tubule main body primordium; presumptive embryonic/larval muscle system; embryonic somatic muscle; embryonic myoblast; midgut constriction 1; presumptive embryonic/larval digestive system.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; Elongated TPR repeat-containing domain; Tetratricopeptide repeat-containing; Tetratricopeptide-like helical; Zinc finger, RING-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period.