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|Flybase description||The gene Thiolester containing protein II is referred to in FlyBase by the symbol Dmel\TepII (CG7052, FBgn0041182).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: peptidase inhibitor activity.
There is experimental evidence that it is involved in the biological process: defense response to Gram-negative bacterium; antibacterial humoral response; phagocytosis, engulfment.
5 alleles are reported.
No phenotypic data is available.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: A-macroglobulin complement component; Alpha-2-macroglobulin; Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-2-macroglobulin, conserved site; Alpha-2-macroglobulin, thiol-ester bond-forming; Alpha-macroglobulin, receptor-binding; Terpenoid cylases/protein prenyltransferase alpha-alpha toroid.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed during late larval stages, at stages throughout the pupal period.