Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name TepII
Flybase description The gene Thiolester containing protein II is referred to in FlyBase by the symbol Dmel\TepII (CG7052, FBgn0041182).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -8.244 -3.8962 -15.076874 -17.6197 -19.917733 -8.5853 -2.2383 -11.188413
    Affimetrix absolute value 5.374 5.684 4.273 4.29 4.532 5.479 7.466 4.87
    Affymetric present call in "x" number of chips 2 3 0 0 0 2 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: peptidase inhibitor activity.
There is experimental evidence that it is involved in the biological process: defense response to Gram-negative bacterium; antibacterial humoral response; phagocytosis, engulfment.
5 alleles are reported.
No phenotypic data is available.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: A-macroglobulin complement component; Alpha-2-macroglobulin; Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-2-macroglobulin, conserved site; Alpha-2-macroglobulin, thiol-ester bond-forming; Alpha-macroglobulin, receptor-binding; Terpenoid cylases/protein prenyltransferase alpha-alpha toroid.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed during late larval stages, at stages throughout the pupal period.