Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name TepI
Flybase description The gene Thiolester containing protein I is referred to in FlyBase by the symbol Dmel\TepI (CG18096, FBgn0041183).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -44.3835 -30.6133 -42.319912 -46.4427 -54.760076 -50.9071 -60.54681 -46.025879
    Affimetrix absolute value 2.966 2.693 2.788 2.86 2.984 2.893 2.669 2.741
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: endopeptidase inhibitor activity.
There is experimental evidence that it is involved in the biological process: antibacterial humoral response.
3 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: A-macroglobulin complement component; Alpha-2-macroglobulin; Alpha-2-macroglobulin, N-terminal; Alpha-2-macroglobulin, N-terminal 2; Alpha-2-macroglobulin, conserved site; Alpha-2-macroglobulin, thiol-ester bond-forming; Alpha-macroglobulin, receptor-binding; Terpenoid cylases/protein prenyltransferase alpha-alpha toroid.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.
Peak expression observed during late larval stages, during early pupal stages.