Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Pkd2
Flybase description The gene Polycystic kidney disease gene-2 is referred to in FlyBase by the symbol Dmel\Pkd2 (CG6504, FBgn0041195).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -57.7913 -30.8475 -38.753681 -49.5434 -64.048131 -57.2274 -45.19176 -43.884778
    Affimetrix absolute value 2.564 2.703 2.919 2.76 2.793 2.726 3.075 2.814
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 1 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: cation channel activity.
There is experimental evidence that it is involved in the biological process: larval feeding behavior; smooth muscle contraction; sperm competition; sperm motility; sperm storage; spermatogenesis.
17 alleles are reported.
The phenotypes of these alleles are annotated with: flagellum; spermatozoon.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Polycystin cation channel, PKD1/PKD2.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.
Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.