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|Flybase description||The gene Ku80 is referred to in FlyBase by the symbol Dmel\Ku80 (CG18801, FBgn0041627).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ATP-dependent DNA helicase activity; single-stranded DNA-dependent ATP-dependent DNA helicase activity.
There is experimental evidence that it is involved in the biological process: telomere maintenance.
3 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: DNA helicase, ATP-dependent, Ku type; DNA helicase, ATP-dependent, Ku80 subunit; Ku, C-terminal; Ku70/Ku80 C-terminal arm; Ku70/Ku80, N-terminal alpha/beta; Spen Paralogue and Orthologue SPOC, C-terminal-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.