Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name frc
Flybase description The gene fringe connection is referred to in FlyBase by the symbol Dmel\frc (CG3874, FBgn0042641).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -0.3769 3.3722 1.27364 -0.3959 -0.653563 0.3906 -1.28168 0.222968
    Affimetrix absolute value 8.349 9.35 8.484 8.312 8.383 8.638 8.213 8.154
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: UDP-galactose transmembrane transporter activity; UDP-glucuronic acid transmembrane transporter activity; antiporter activity; UDP-N-acetylglucosamine transmembrane transporter activity; UDP-glucose transmembrane transporter activity; UDP-xylose transmembrane transporter activity.
There is experimental evidence for 11 unique biological process terms, many of which group under: nitrogen compound transport; localization; multicellular organismal development; pyrimidine nucleotide-sugar transport; system development; transmembrane transport; embryonic pattern specification; sensory organ development; regionalization; pattern specification process; organic substance transport.
21 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system subdivision; adult segment; organ system; external compound sense organ; postalar bristle; acellular anatomical structure; thoracic segment; peripheral nervous system; integumentary plate; extended germ band embryo.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Domain of unknown function DUF250.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.
This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.
The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.