Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name PGRP-SB2
Flybase description The gene PGRP-SB2 is referred to in FlyBase by the symbol Dmel\PGRP-SB2 (CG9697, FBgn0043577).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -36.4586 -19.6813 -29.358652 -41.1367 -45.294366 -36.1507 -41.07363 -30.215207
    Affimetrix absolute value 3.234 3.331 3.343 3.062 3.257 3.392 3.199 3.395
    Affymetric present call in "x" number of chips 1 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: peptidoglycan binding.
Based on sequence similarity, it is predicted to be involved in the biological process: immune response.
2 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: N-acetylmuramoyl-L-alanine amidase domain; Peptidoglycan recognition protein; Peptidoglycan recognition protein family domain, metazoa/bacteria; Peptidoglycan recognition protein, PGRP-S.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected.
Peak expression observed during early pupal stages.