Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name mask
Flybase description The gene multiple ankyrin repeats single KH domain is referred to in FlyBase by the symbol Dmel\mask (CG33106, FBgn0043884).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -7.2837 -2.9178 -9.491672 -6.4301 -15.281099 -7.7069 -5.94315 -14.479397
    Affimetrix absolute value 5.578 6.087 4.953 5.77 4.885 5.618 6.053 4.532
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: structural constituent of cytoskeleton.
There is experimental evidence that it is involved in the biological process: transmembrane receptor protein tyrosine kinase signaling pathway; compound eye photoreceptor cell differentiation; cell proliferation; cellular process; antimicrobial humoral response.
26 alleles are reported.
The phenotypes of these alleles are annotated with: eye-antennal disc; eye; trichogen cell; embryonic/larval digestive system; heart primordium; mesothoracic tergum; ommatidial precursor cluster.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; K Homology; K Homology, type 1; K Homology, type 1, subgroup.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.