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|Flybase description||The gene domeless is referred to in FlyBase by the symbol Dmel\dome (CG14226, FBgn0043903).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: transmembrane receptor activity.
There is experimental evidence that it is involved in the biological process: blastoderm segmentation; morphogenesis of an epithelium; hindgut morphogenesis; border follicle cell migration; positive regulation of cell proliferation; long-term memory; JAK-STAT cascade; open tracheal system development; compound eye morphogenesis.
49 alleles are reported.
The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: organ system; organ system subdivision; multicellular structure; spiracle; integumentary specialisation; portion of tissue; adult segment; non-connected developing system; embryonic hindgut; epithelial cell; external compound sense organ.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.