Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name fdl
Flybase description The gene fused lobes is referred to in FlyBase by the symbol Dmel\fdl (CG8824, FBgn0045063).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -7.9826 -5.9871 -16.159159 -13.8801 -30.279452 -20.5944 -12.72054 -22.75979
    Affimetrix absolute value 5.455 5.053 4.165 4.603 3.88 4.217 4.892 3.811
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: beta-N-acetylglucosaminidase activity.
There is experimental evidence that it is involved in the biological process: brain development; N-glycan processing.
12 alleles are reported.
The phenotypes of these alleles are annotated with: protocerebral bridge; mushroom body beta-lobe.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Acetylhexosaminidase, subunit a/b; Glycoside hydrolase, family 20; Glycoside hydrolase, family 20, catalytic core; Glycoside hydrolase, subgroup, catalytic core; Glycoside hydrolase, superfamily.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.