Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Stim
Flybase description The gene Stromal interaction molecule is referred to in FlyBase by the symbol Dmel\Stim (CG9126, FBgn0045073).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.4259 2.7304 -0.25601 1.3932 -0.900808 1.1731 2.0573 0.325823
    Affimetrix absolute value 9.638 9.058 8.261 8.859 8.176 8.788 9.579 8.245
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: calcium-induced calcium release activity; store-operated calcium channel activity.
There is experimental evidence that it is involved in the biological process: bristle development; positive regulation of calcium ion transport via store-operated calcium channel activity; positive regulation of NFAT protein import into nucleus; activation of store-operated calcium channel activity; imaginal disc-derived wing morphogenesis.
12 alleles are reported.
The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system subdivision; adult segment; organ system; thoracic segment; external compound sense organ; adult; embryonic/larval fat body; embryo-derived cell-line; imaginal precursor; cultured cell-line; wing margin bristle; integumentary plate; peripheral nervous system.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: EF-hand-like domain; Sterile alpha motif domain; Sterile alpha motif homology; Sterile alpha motif, type 2; Sterile alpha motif-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.