Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG31183
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG31183 (FBgn0051183).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -8.0037 -3.0308 -4.013343 -4.9072 -7.087228 -8.9708 -8.71673 -5.486117
    Affimetrix absolute value 5.415 6.073 6.202 6.092 5.966 5.408 5.434 5.863
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: natriuretic peptide receptor activity; guanylate cyclase activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: cyclic nucleotide biosynthetic process; protein phosphorylation; intracellular signal transduction.
5 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site; Extracellular ligand-binding receptor; Natriuretic peptide receptor; Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages, during late larval stages, during late pupal stages, in adult male stages.