Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name GluRIIE
Flybase description The gene Glutamate receptor IIE is referred to in FlyBase by the symbol Dmel\GluRIIE (CG31201, FBgn0051201).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.4977 -16.5061 -36.867311 -35.5324 -58.955587 -50.5217 -14.72993 -25.927439
    Affimetrix absolute value 7.112 3.605 3.031 3.242 2.908 2.906 4.692 3.676
    Affymetric present call in "x" number of chips 3 3 0 1 0 0 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: kainate selective glutamate receptor activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: ion transport.
11 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; neuromuscular junction; mesothoracic tergum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Extracellular ligand-binding receptor; Ionotropic glutamate receptor; NMDA receptor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 12-24 hour embryonic stages, during late pupal stages.