Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Mrtf
Flybase description The gene Myocardin-related transcription factor is referred to in FlyBase by the symbol Dmel\Mrtf (CG32296, FBgn0052296).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -13.229 -7.7852 -12.287546 -6.1607 -20.384144 -10.4385 -11.58533 -14.863436
    Affimetrix absolute value 4.683 4.662 4.59 5.845 4.464 5.186 5.064 4.435
    Affymetric present call in "x" number of chips 2 3 2 3 2 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: nucleic acid binding.
There is experimental evidence that it is involved in the biological process: mesodermal cell migration; regulation of cell division; border follicle cell migration; actin cytoskeleton organization; cellular response to hypoxia; imaginal disc-derived wing morphogenesis; open tracheal system development.
30 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; late extended germ band embryo; adult segment; organ system subdivision; non-connected developing system; portion of tissue; extended germ band embryo; tracheal branch primordium; multicellular structure; thoracic segment.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: DNA-binding SAP; RPEL repeat.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 and 12-18 hour embryonic stages.